New Partnership in Support of Data Analysis for Next Gen Sequencing

  • Do you need to analyze Next Generation Sequencing (NGS) datasets?
  • Are you concerned about rigor and reproducibility?
  • Would you like assistance with CLC Genomics Workbench workflows?

The Molecular Biology Information Service of the Health Sciences Library System (HSLS-MBIS), with support from the Institute for Precision Medicine, licenses CLC Genomics Workbench from QIAGEN for use by the University of Pittsburgh community. This software streamlines analysis of NGS datasets such as RNA-Seq, Exome Sequencing, and ChIP-Seq. Given that the analytical workflows for this software suite are complex and the emphasis on rigor and reproducibility in data analysis is increasing, HSLS-MBIS has collaborated with the Genomics Analysis Core of the Department of Biomedical Informatics (DBMI-GAC) to provide comprehensive assistance with the use of CLC Genomics Workbench for NGS data analysis.

Investigators can learn about data preparation, data importation, and CLC Genomics Workbench software capabilities at an in-depth, three-hour monthly workshop offered by HSLS-MBIS. If there is a need for additional guidance, investigators may receive up to five hours of free, individualized assistance for CLC Genomics Workbench-related data analysis provided by a DBMI-GAC analyst. Prerequisites for this assistance are workshop attendance and completion of an online questionnaire about the specific project. If needed, the DBMI-GAC analyst may continue to provide further support on a fee-for-service basis.

Note that HSLS-MBIS and the DBMI-GAC analyst provide instruction and consultation in how to use CLC Genomics Workbench software, including best practices, and advice on software parameter settings appropriate to the specific project. We do not engage in interpretive consultation and do not perform the analysis for the user. If you need data analysis performed for you, contact the GAC Director, Uma Chandran, to discuss your project.

Additional details are available, including the project questionnaire. Register for access to CLC Genomics Workbench. Check the HSLS Class Calendar for upcoming workshops on RNA-seq Analysis on CLC Genomics Workbench. Contact HSLS-MBIS with any questions.

~Carrie Iwema