FY 22 Annual Report

Health Sciences Library System


Advanced Literature Searches

Librarians design and build complex literature searches to support research within the health sciences. In FY 22, 240 literature searches were completed, with 55% requiring the use of more than one database (total number of databases searched = 430).

The School of Medicine accounted for 35% of searches, followed by UPMC residents/fellows (17%), School of Nursing (14%), School of Public Health (12%), School of Health and Rehabilitation Sciences (12%), School of Dental Medicine (3%), and the School of Pharmacy (3%). The remaining 4% were searches completed for individuals outside the schools of the health sciences.


Two librarians serve as co-liaisons to the Institutional Animal Care and Use Committee (IACUC)—regularly attending monthly committee meetings, offering trainings to researchers and committee members, and completing literature searches that are required in protocol submissions. In FY 22, 34 IACUC protocols were supported through HSLS literature searches.

HSLS Impact:

Dr. Michael Pinsky from the Department of Critical Care Medicine noted that a literature search to support a modification of his IACUC protocol resulted in changes to the lab’s proposed procedures and model.

Funding for this protocol is through the Department of Defense (DOD), Grant name: Trauma Care in a Rucksack (TRACIR).

Systematic Reviews

Librarians contributed work to 51 systematic review projects. As co-investigators on these complex research projects, librarians conducted in-depth discussions with investigators to assist in the creation or revision of project protocols; designed, built, and documented complex search strings for use in bibliographic databases; and assisted in the writing and editing of abstracts and manuscripts. The Systematic Review Program received 59 requests for librarian assistance with new systematic review projects, averaging 4.9 requests per month. Faculty from the School of Medicine submitted 32% of requests, followed by faculty from the School of Health and Rehabilitation Sciences (31%), UPMC residents or fellows (25%), School of Public Health (8%), and the School of Nursing (3%). Sixteen consultations were provided to patrons on use of the systematic review software licensed by HSLS (DistillerSR). Beginning in February 2022, all submitted protocols were subject to internal review by two senior members of the SR Program, and patrons may be required to revise their protocols before an HSLS librarian is assigned to the review project. The purpose of this internal review is to ensure that the protocol meets current standards for the design and conduct of complex reviews and contains the detailed topic information required for HSLS librarians to develop comprehensive literature searches.

Molecular Biology Information Service

The Molecular Biology Information Service (MBIS) provides access to bioinformatics resources via software procurement, implementation, and training to assist biomedical scientists. MBIS teaches hands-on workshops and offers one-on-one or group consultations on multiple bioinformatics software covering next gen sequencing, genetic variation, Sanger sequence analysis, microarrays, gene regulation, pathways, and genes, proteins, and diseases.

HSLS provided 13 commercial bioinformatics software and database packages, with 8,107 registered users. In FY 22, two additional seats of the next generation sequencing software Partek Flow were added. MBIS specialists offered 93 consults to support research within the health sciences, and 397 Pitt publications cited HSLS MBIS licensed software.

Data Services

Librarians offer consultations and customized instruction to help organize and describe research data, to write data management and sharing plans, to preserve data for long-term access, and to locate data for reuse. Librarians in this service also oversee the Pitt Data Catalog, which to date includes 97 records.

Librarians collaborated with the Office of Sponsored Programs to prepare the health sciences research community to meet the requirements of the new NIH Policy for Data Management and Sharing. Additionally, they offered 20 consults on topics including locating specific datasets, writing data management and sharing plans, and citing data.

Scholarly Publishing and Communication Services

HSLS supports dissemination of all types of research outputs including journal publications, preprints, protocols, datasets, and software. Librarians offer consultations and customized instruction on writing up and promoting research, open access publishing, and author rights.

HSLS increased support for scholarly publishing and research impact, promoting a librarian to focus in this area. Librarians facilitated discussions with the Associate Deans of Research within the health sciences regarding tools for departmental publication reporting for annual reviews. They provided 66 consults on topics including using My Bibliography for grant reporting, journal evaluation, metrics for measuring impact, and copyright.



  1. Advani P, Advani S, Nayak P, VonVille HM, Diamond P, Burnett J, Brewster AM, Vernon SW. Racial/ethnic disparities in use of surveillance mammogram among breast cancer survivors: a systematic review. J Cancer Surviv. 2022 Jun;16(3):514-530. doi: 10.1007/s11764-021-01046-2. Epub 2021 May 13. PMID: 33982233.
  2. Barot, N., Batra, K., Zhang, J., Klem, M. L., Castellano, J., Gonzalez-Martinez, J., & Bagic, A. (2022). Surgical outcomes between temporal, extratemporal epilepsies and hypothalamic hamartoma: systematic review and meta-analysis of MRI-guided laser interstitial thermal therapy for drug-resistant epilepsy. Journal of neurology, neurosurgery, and psychiatry, 93(2), 133–143. https://doi.org/10.1136/jnnp-2021-326185
  3. Bhuiyan, M., Young, C. B., Jahan, I., Hasan, M. N., Fischer, S., Meor Azlan, N. F., Liu, M., Chattopadhyay, A., Huang, H., Kahle, K. T., Zhang, J., Poloyac, S. M., Molyneaux, B. J., Straub, A. C., Deng, X., Gomez, D., & Sun, D. (2022). NF-κB Signaling-Mediated Activation of WNK-SPAK-NKCC1 Cascade in Worsened Stroke Outcomes of Ang II-Hypertensive Mice. Stroke, 53(5), 1720–1734. https://doi.org/10.1161/STROKEAHA.121.038351
  4. Bise, Christopher Gene and Cupler, Zachary and Mathers, Sean and Turner, Rose and Sundaram, Meenakshi and Catalani, Beatriz and Dahler, Sarah and Popchak, Adam and Schneider, Michael J., Face to Face Telehealth Interventions in the Treatment of Low Back Pain: A Systematic Review. CTCP-D-22-00121. 3 Mar. 2022, http://dx.doi.org/10.2139/ssrn.4029450
  5. Brady MB, VonVille HM, White JF, Martin EM, Raabe NJ, Slaughter JM, Snyder GM. Transmission visualizations of healthcare infection clusters: A scoping review. Antimicrob Steward Healthc Epidemiol. 2022 Jun 15;2(1):e92. doi: 10.1017/ash.2022.237. PMID: 36483443; PMCID: PMC9726548.
  6. Brick R, Turner R, Bender C, Douglas M, Eilers R, Ferguson R, Leland N, Lyons KD, Toto P, Skidmore E. Impact of non-pharmacological interventions on activity limitations and participation restrictions in older breast cancer survivors: A scoping review. J Geriatr Oncol. 2022 Mar;13(2):132-142. doi: 10.1016/j.jgo.2021.09.010. Epub 2021 Sep 29. PMID: 34598902.
  7. Butler RA, White DB, Arnold RM, Cook T, Klein-Fedyshin M, Mohan D, Seaman JB. Delphi-endorsed communication skills clinicians need to care for incapacitated hospitalized patients. ATS Scholar 3(2) 2022. https://doi.org/10.34197/ats-scholar.2021-0136OC
  8. Cavanaugh R, Kravetz C, Jarold L, Quique Y, Turner R, Evans WS. Is There a Research-Practice Dosage Gap in Aphasia Rehabilitation? Am J Speech Lang Pathol. 2021 Sep 23;30(5):2115-2129. doi: 10.1044/2021_AJSLP-20-00257. Epub 2021 Aug 19. PMID: 34411485; PMCID: PMC8702848.
  9. Connor SE, Jonkman LJ, Covvey JR, Kahaleh AA, Park SK, Ryan M, Klein-Fedyshin M, Golchin N, Veillard RB. A Systematic Review of Global Health Assessment for Education in Healthcare Professions. Annals of Global Health. 2022; 88(1): 1. DOI: https://doi.org/10.5334/aogh.3389
  10. Contaxis N, Clark J, Dellureficio A, Gonzales S, Mannheimer S, Oxley PR, Ratajeski MA, Surkis A, Yarnell AM, Yee M, and Holmes K. (2022). Ten simple rules for improving research data discovery. PLOS Computational Biology. 18(2):e1009768. doi.org/10.1371/journal.pcbi.1009768
  11. Cowles, K., Glusker, A., Gogan, A., Lillich, A., Sheppard, M., Vitale, E., Waltman, L., Wilson, T., & Wilson, A. Crowdsourcing and Collaboration: Academic Libraries as Partners in NNLM’s #CiteNLM Wikipedia Edit-a-Thons. October 2021. Wikipedia and Academic Libraries: A Global Project, Eds. Laurie M. Bridges, Ray Pun and Roberto Arteaga. https://www.bibliovault.org/BV.book.epl?ISBN=9781607856702
  12. Dahm JJ, Reese JG. Sharing electronically and accessibly in library-led instruction. J Med Libr Assoc. 2021 Oct 1;109(4):690-692. doi: 10.5195/jmla.2021.1361. PMID: 34858106; PMCID: PMC8608205.
  13. Escobar-Viera, C.G., Melcher, E.M., Miller, R.S., Whitfield, D.L., Gordon, J.D., Jacobson, D.A., Ballard, A.J., Rollman, B.L., Pagoto, S. (2021). A systematic review of the engagement with social media–delivered interventions for improving health outcomes among sexual and gender minorities. Internet Interventions, 25. doi: 10.1016/j.invent.2021.100428
  14. Ferrari R, Cong G, Chattopadhyay A, Xie B, Assaf E, Morder K, Calderon MJ, Watkins SC, Sachdev U. Attenuated cell-cycle division protein 2 and elevated mitotic roles of polo-like kinase 1 characterize deficient myoblast fusion in peripheral arterial disease. Biochem Biophys Res Commun. 2022 Apr 3;609:163-168. doi: 10.1016/j.bbrc.2022.03.161. Epub ahead of print. PMID: 35436627.
  15. Gabrielson, SW. Getting Familiar with Altmetrics. MLAConnect. 2022, June 16. Retrieved from https://www.mlanet.org/p/cm/ld/fid=1122&&blogaid=4016
  16. Govas, P., Ketchum, A., Kazi, R., Gordon, B. R., & Carroll, B. T. (2022). Pain Intensity Assessment Scales for Dermatologic Surgery Patients: A Systematic Review. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 48(2), 232–238. https://doi.org/10.1097/DSS.0000000000003353
  17. Govas, P., Ramanathan, D., Ketchum, A., & Carroll, B. T. (2022). Systematic review reporting quality within dermatology: Bibliometric trends compared with general medicine and general surgery from 2008 to 2017. Journal of the American Academy of Dermatology, 87(1), 225-228. https://doi.org/10.1016/j.jaad.2021.07.056
  18. Hanmer J, Cizik AM, Gulek BG, McCracken P, Swart ECS, Turner R, Kinsky SM. A scoping review of US insurers’ use of patient-reported outcomes. Am J Manag Care. 2022 Jun 1;28(6):e232-e238. doi: 10.37765/ajmc.2022.89162. PMID: 35738231.
  19. Harper AE, Rouch S, Leland NE, Turner RL, Mansbach WE, Day CE, Terhorst L. A Systematic Review of Tools Assessing the Perspective of Caregivers of Residents With Dementia. J Appl Gerontol. 2022 Apr;41(4):1196-1208. doi: 10.1177/07334648211028692. Epub 2021 Jul 7. PMID: 34229505.
  20. Liu Q, Bhuiyan MIH, Liu R, Song S, Begum G, Young CB, Foley LM, Chen F, Hitchens TK, Cao G, Chattopadhyay A, He L, Sun D. Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function. J Neuroinflammation. 2021 Aug 28;18(1):187. doi: 10.1186/s12974-021-02234-8. PMID: 34454529; PMCID: PMC8403348.
  21. Mains-Mason JB, Ufomata E, Peebles JK, Dhar CP, Sequeira G, Miller R, Folb B, Eckstrand KL. Knowledge Retention and Clinical Skills Acquisition in Sexual and Gender Minority Health Curricula: A Systematic Review. Acad Med. 2022 Jun 14. doi: 10.1097/ACM.0000000000004768. Epub ahead of print. PMID: 35703197.
  22. Patterson, P. D., Mcilvaine, Q. S., Nong, L., Liszka, M. K., Miller, R. S., Guyette, F. X., & Martin-Gill, C. (2022). Masking by health care and public safety workers in non-patient care areas to mitigate SARS-CoV-2 infection: A systematic review. Journal of the American College of Emergency Physicians Open, 3(2), e12699. https://doi.org/10.1002/emp2.12699
  23. Ratajeski MA & Miller RS. Adapting to Changes in Publishing When Searching for Alternatives and Reporting on Animal Research: A Librarian’s Perspective. Alternatives to laboratory animals: ATLA, 2611929211072862. 25 Feb. 2022, doi:10.1177/02611929211072862
  24. Ratajeski, M.A. & Miller, R. (2022). Librarians and the IACUC: Practical approaches for performing alternatives searches and providing support. In S.M. Harnett & L.P. Cantwell (Eds.), Finding your seat at the table: Roles for librarians on institutional regulatory boards and committees. United States:Rowman & Littlefield.
  25. Ross NE, Webster TG, Tastenhoye CA, Hauspurg AK, Foust JE, Gopalan PR, Hatters Friedman S. Reproductive Decision-Making Capacity in Women With Psychiatric Illness: A Systematic Review. J Acad Consult Liaison Psychiatry. 2022 Jan-Feb;63(1):61-70. doi: 10.1016/j.jaclp.2021.08.007. Epub 2021 Aug 27. PMID: 34461294; PMCID: PMC8792197.
  26. Samuel S, Moore M, Sheridan H, Sorensen C, Patterson B. Touring a Data Curation Network Primer: A Focus on Neuroimaging Data. Journal of eScience Librarianship 2021; 10(3): e1204. https://doi.org/10.7191/jeslib.2021.1204.
  27. Sheridan H, Dellureficio AJ, Ratajeski MA, Mannheimer S, Wheeler TR. Data Curation through Catalogs: A Repository-Independent Model for Data Discovery. Journal of eScience Librarianship 2021; 10(3): e1203. https://doi.org/10.7191/jeslib.2021.1203.
  28. Sivakanthan S, Candiotti JL, Sundaram AS, Duvall JA, Sergeant JJG, Cooper R, Satpute S, Turner RL, Cooper RA. Mini-review: Robotic wheelchair taxonomy and readiness. Neurosci Lett. 2022 Feb 16;772:136482. doi: 10.1016/j.neulet.2022.136482. Epub 2022 Jan 29. PMID: 35104618; PMCID: PMC8887066.
  29. Song, S., Huang, H., Guan, X., Fiesler, V., Bhuiyan, M., Liu, R., Jalali, S., Hasan, M. N., Tai, A. K., Chattopadhyay, A., Chaparala, S., Sun, M., Stolz, D. B., He, P., Agalliu, D., Sun, D., & Begum, G. (2021). Activation of endothelial Wnt/β-catenin signaling by protective astrocytes repairs BBB damage in ischemic stroke. Progress in neurobiology, 199, 101963. https://doi.org/10.1016/j.pneurobio.2020.101963
  30. Yousef S, Sultan I, VonVille HM, Kahru K, Arnaoutakis GJ. Surgical management for mechanical complications of acute myocardial infarction: a systematic review of long-term outcomes. Ann Cardiothorac Surg. 2022;11(3):239-251. doi:10.21037/acs-2021-ami-20
  31. Zheng W, D’Aiuto L, Demers MJ, Muralidaran V, Wood JA, Wesesky M, Chattopadhyay A, Nimgaonkar VL. Insights into bioinformatic approaches for repurposing compounds as anti-viral drugs. Antivir Chem Chemother. 2021 Jan-Dec;29:20402066211036822. doi: 10.1177/20402066211036822. PMID: 34463534; PMCID: PMC8411619.


  1. Cowles, K. Citizen Science: Transforming Scientific Research Through Public Participation. April 2022. Pittsburgh, PA: University of Pittsburgh Year of Data & Society invited lecture.
  2. Fort, M and Kim, YM (2021, October 28-30). Beyond the Practice of Medicine–Selection of Medical Medals from the HSLS Collection. Pennsylvania Association of Numismatists 2021 Fall Convention. Monroeville, PA, United States.
  3. Gabrielson S, Iwema C, Ratajeski M, Sheridan H, Yates F. More than Manuscripts: Redesigning a Scholarly Communication Guide to Include Multiple Research Outputs. Lightning talk presented by lead author at Medical Library Association Annual Meeting, May 3-6, 2022.
  4. Hoffman BL, Manganello JA, Chu K, Sidani JE, VonVille HM, Miller E, Felter EM, Burke JG. Exposure to Fictional Television and Health: A Scoping Review. Poster Presentation. 2022 Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine. Baltimore, MD. April 7, 2022.
  5. Iwema, C. (2021, November 4). Making Sense of Basic Science: A Reflection on Lab Culture. Basic Science Caucus, Medical Library Association.
  6. Iwema, C. (2021, October 28). All Things Preprints: An Introduction. Virtual Scholarly Communication Caucus Shop Talk Session #2, Medical Library Association.
  7. Mahoney, A., Turner, R., O’Donnell, M., Coyle, J., Skoretz, S., White, K. Synthesizing the Evidence on Interventions that Bridge Hospitalized Infants from Non-Oral to Oral Feeding. Proposal accepted at the 2021 Annual Convention of the American Speech-Language-Hearing Association, Washington, DC. Session Number 4730V.
  8. Suppok, R. (2022, May 4-6). Providing EndNote instruction through interactive tutorials [Conference presentation]. Medical Library Association Annual Conference, New Orleans, LA, United States.
  9. Wilson T, (2021, October 19). Data Zines: A Hands-On Approach to Community Curiosities. ACRL Data Literacy Cookbook Panel [Panelist]. ACRL DSS Numeric & Geospatial Data Services Discussion Group.
  10. Zerfas IL, Hume NE, Wong A, Klein-Fedyshin M, Smithburger PL, Buckley M, Devlin J, Kane (Gill) S. Pain, Agitation, Delirium, Immobility Guideline Implementation Strategies and Patient Outcomes: A Systematic Review and Meta-Analysis. SCCM (Society of Critical Care Medicine) Abstract and Case Report Presentation. Virtual Meeting April 18-21, 2022.


  1. American Psychiatric Association, DSM-5 Text Revision. (Michele Klein-Fedyshin)
  2. Becker-Krail, D. D. et al. Astrocyte Molecular Clock Function in the Nucleus Accumbens Is Important for Reward-Related Behavior. Biol. Psychiatry 92, 68–80 (2022). (Molecular Biology Information Service)
  3. Bhuiyan, M. I. H. et al. NF-κB Signaling-Mediated Activation of WNK-SPAK-NKCC1 Cascade in Worsened Stroke Outcomes of Ang II-Hypertensive Mice. Stroke 53, 1720–1734 (2022). (Molecular Biology Information Service)
  4. Biradar, S. et al. Nef dimerization defect abrogates HIV viremia and associated immune dysregulation in the Bone Marrow-Liver-Thymus-Spleen (BLTS) humanized mouse model. BioRxiv (2021) doi:10.1101/2021.01.21.427631. (Molecular Biology Information Service)
  5. Chauhan, B. K., Medsinge, A., Scanga, H. L., Chu, C. T. & Nischal, K. K. Transcriptome from opaque cornea of Fanconi anemia patient uncovers fibrosis and two connected players. Mol. Genet. Metab. Rep. 26, 100712 (2021). (Ansuman Chattopadhyay)
  6. Chen, S., Lathrop, K. L., Kuwajima, T. & Gross, J. M. Retinal ganglion cell survival after severe optic nerve injury is modulated by crosstalk between Jak/Stat signaling and innate immune responses in the zebrafish retina. Development 149, (2022). (Molecular Biology Information Service)
  7. Cruz, D. F., Mitash, N., Mu, F., Farinha, C. M. & Swiatecka-Urban, A. Differential Gene Expression Analysis Reveals Global LMTK2 Regulatory Network and Its Role in TGF-β1 Signaling. Front. Oncol. 11, 596861 (2021). (Sri Chaparala and Ansuman Chattopadhyay)
  8. Delgado, E. R. et al. Scaffolding protein IQGAP1 is dispensable, but its overexpression promotes hepatocellular carcinoma via YAP1 signaling. Mol. Cell. Biol. 41, (2021). (Molecular Biology Information Service)
  9. Gabriel, G. C. Genetic and Epigenetic Basis for Brain Abnormalities and Neurobehavioral Deficits in a Mouse Model of Hypoplastic Left Heart Syndrome. (2022). Doctoral Dissertation, University of Pittsburgh. (Unpublished) (Molecular Biology Information Service)
  10. Herbstsomer RA, Stahl ST. Cross-Cultural Experiences of Hospice and Palliative Care Services: A Thematic Analysis. Omega (Westport). 2021 Dec;84(2):551-566. doi: 10.1177/0030222820904205. Epub 2020 Feb 20. PMID: 32077377. (Michele Klein-Fedyshin)
  11. Leach, L. L., Hanovice, N. J., George, S. M., Gabriel, A. E. & Gross, J. M. The immune response is a critical regulator of zebrafish retinal pigment epithelium regeneration. Proc Natl Acad Sci USA 118, (2021). (Molecular Biology Information Service)
  12. Liu, C.-H. et al. Lipopolysaccharide-Mediated Chronic Inflammation Promotes Tobacco Carcinogen-Induced Lung Cancer and Determines the Efficacy of Immunotherapy. Cancer Res. 81, 144–157 (2021). (Molecular Biology Information Service)
  13. Liu, Y. et al. Inhibition of TGFβ-activated kinase 1 promotes inflammation-resolving microglial/macrophage responses and recovery after stroke in ovariectomized female mice. Neurobiol. Dis. 151, 105257 (2021). (Molecular Biology Information Service)
  14. Lu, F., Leach, L. L. & Gross, J. M. mTOR activity is essential for retinal pigment epithelium regeneration in zebrafish. PLoS Genet. 18, e1009628 (2022) (Molecular Biology Information Service)
  15. Song, S. et al. Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice. Commun. Biol. 5, 35 (2022). (Molecular Biology Information Service)
  16. Song, S. et al. Microglial-oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury. Res. Sq. (2022) doi:10.21203/rs.3.rs-1790060/v1. (Molecular Biology Information Service)
  17. Treble-Barna, A. et al. Acute Brain-DerivedNeurotrophic Factor DNA Methylation Trajectories in Cerebrospinal Fluid and Associations With Outcomes Following Severe Traumatic Brain Injury in Adults. Neurorehabil. Neural Repair 35, 790–800 (2021). (Ansuman Chattopadhyay)
  18. Vats, A., Xi, Y., Feng, B., Clinger, O. D., St Leger, A. J., Liu, X., Ghosh, A., Dermond, C. D., Lathrop, K. L., Tochtrop, G. P. & Picaud, S. Nonretinoid chaperones improve rhodopsin homeostasis in a mouse model of retinitis pigmentosa. JCI Insight. 2022;7(10):e153717. https://doi.org/10.1172/jci.insight.153717 (2022). (Sri Chaparala)
  19. Zuppo, D. A. et al. Foxm1 drives cardiomyocyte proliferation in adult zebrafish after cardiac injury. BioRxiv (2022) doi:10.1101/2022.06.22.497073. (Molecular Biology Information Service)