Ingenuity Pathway Analysis
**special Vendor training session**
Wednesday, 12th November 2014
9am – 12pm
Falk Library Classroom 2 (upstairs)
**REGISTER FOR IPA HERE**
This special workshop will replace the workshops on Pathway Analysis Tools originally scheduled for 1-3 pm on 11/5/2014 and 11/12/2014.
9-9:15 am:
- What is IPA?
- Why use IPA?
- Ingenuity Knowledge Base
9:45-10:45 am:
Use the Search & Explore interface to access IPA’s Knowledge Base for deep investigation of any gene, protein, or metabolite and how to further refine gene sets isolated from large-scale data analyses.
- Search for a Gene/Chemical/function and drug
- Use Build and Overlay tools to construct pathways based on published experimental evidence
- Performing an Advanced Search: Limiting results to a molecule type, family or subcellular location
- Add molecules from search results to a pathway
- Use the MAP tool to run in silico simulation based on your curated Knowledge Base relationships
10:45-11:45 am:
Using an example gene expression dataset the basic to intermediate IPA functionalities will be covered.
- Upload single and multiple observation datasets
- Find and interpret the direction and biological effect of your expression data
- Find and interpret the most relevant canonical pathways and predict pathways effects
- Identify predicted upstream regulators (transcription factors, miRNA, receptors, drugs, etc.)
- Understand the basics of the Network generation algorithm and how to interpret the network result
- Understand Regular Effects
11:45 am-noon:
- Questions and Answers if time permits