{"id":5292,"date":"2024-03-13T13:37:33","date_gmt":"2024-03-13T18:37:33","guid":{"rendered":"https:\/\/info.hsls.pitt.edu\/molbio\/?p=5292"},"modified":"2024-03-28T10:04:19","modified_gmt":"2024-03-28T15:04:19","slug":"march-20-gene-regulation","status":"publish","type":"post","link":"https:\/\/info.hsls.pitt.edu\/molbio\/2024\/03\/13\/march-20-gene-regulation\/","title":{"rendered":"March 20: Gene Regulation"},"content":{"rendered":"<p>Wednesday, March 20, 2024, 1-4 p.m.<br \/>\nHybrid Session: Attend online or in person in the Falk Library Classroom<br \/>\n<a href=\"https:\/\/www.hsls.pitt.edu\/instruction\/gene-regulation\/1126\">Register for Gene Regulation<\/a><\/p>\n<div class=\"field field--name-body field--type-text-with-summary field--label-hidden field__item\">\n<p>This workshop provides an overview of resources and search strategies on transcriptional regulation. Emphasis will be given to HSLS-licensed TRANSFAC\/Match and Correlation Engine software and open-access tools such as the UCSC genome browser and Cistrome data browser.<\/p>\n<\/div>\n<p><!--more--><\/p>\n<div class=\"field field--name-body field--type-text-with-summary field--label-hidden field__item\">\n<p><strong>Target Audience:<\/strong> Experimental biologists seeking to analyze bulk RNA-Seq data generated through experiments or retrieved from a repository such as GEO. The software covered in the workshop operates through a user-friendly, point-and-click graphical user interface, so neither programming experience nor familiarity with the command-line interface is required.<\/p>\n<\/div>\n<div class=\"field field--name-field-learning-objective field--type-string field--label-above\">\n<div class=\"field__label\"><strong>Upon completing this class, you should be able to:<\/strong><\/div>\n<ul class=\"field field--name-field-learning-objective field--type-string field--label-above field__items\">\n<li class=\"field__item\">retrieve information linked with a transcription factor<\/li>\n<li class=\"field__item\">retrieve the promoter sequence for a gene of interest<\/li>\n<li class=\"field__item\">extract transcription regulatory elements&#8211;promoters, enhancers, and silencers associated with a gene of interest<\/li>\n<li class=\"field__item\">identify the transcription factor binding site(s) present in a DNA sequence<\/li>\n<li class=\"field__item\">identify transcription factor binding sites present in a ChIP-Seq dataset (motif discovery)<\/li>\n<li class=\"field__item\">identify upstream regulatory transcription factors for a differentially expressed gene data set<\/li>\n<li class=\"field__item\">start with a gene expression data set and find correlated studies with gene perturbation experiments (knock-out, knock-down, etc.) available in the GEO database<\/li>\n<li class=\"field__item\">start with a ChIP-Seq data set and find factors that have a significant binding overlap with the ChIP-Seq peak set<\/li>\n<\/ul>\n<\/div>\n<div class=\"field field--name-field-recording-status field--type-list-string field--label-inline\">\n<div class=\"field__label\">This class will be recorded and shared with attendees. Class materials will be shared with attendees.<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Wednesday, March 20, 2024, 1-4 p.m.<br \/>\nHybrid Session: Attend online or in person in the Falk Library Classroom<br \/>\n<a href=\"https:\/\/www.hsls.pitt.edu\/instruction\/gene-regulation\/1126\">Register for Gene Regulation<\/a><\/p>\n<p>This workshop provides an overview of resources and search strategies on transcriptional regulation.<\/p>\n<p><a class=\"read-more\" alt= \"March 20: Gene Regulation\" href=\"https:\/\/info.hsls.pitt.edu\/molbio\/2024\/03\/13\/march-20-gene-regulation\/\">Read more&hellip;<\/a><\/p>\n","protected":false},"author":46,"featured_media":5060,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[41],"tags":[],"class_list":["post-5292","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-march-2024"],"_links":{"self":[{"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/posts\/5292","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/users\/46"}],"replies":[{"embeddable":true,"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/comments?post=5292"}],"version-history":[{"count":1,"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/posts\/5292\/revisions"}],"predecessor-version":[{"id":5293,"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/posts\/5292\/revisions\/5293"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/media\/5060"}],"wp:attachment":[{"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/media?parent=5292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/categories?post=5292"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/info.hsls.pitt.edu\/molbio\/wp-json\/wp\/v2\/tags?post=5292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}